Women are almost twice as likely as men to form gallstones especially during the fertile years; the gap narrows after the menopause . The underlying mechanism is female sex hormones; parity, oral contraceptive use and estrogen replacement therapy are established risk factors for cholesterol gallstone formation. Female sex hormones adversely influence hepatic bile secretion and gallbladder function. Estrogens increase cholesterol secretion and diminish bile salt secretion, while progestins act by reducing bile salt secretion and impairing gallbladder emptying leading to stasis. A new 4th generation progestin, drospirenone , used in some oral contraceptives may further heighten the risk of gallstone disease and cholecystectomy; however, the increased risk is quite modest and not likely to be clinically meaningful. 
Many people who have gallstones will experience no symptoms. However, if the gallstones are blocking a bile duct, symptoms can occur. People who experience prolonged pain that lasts for more than five hours, nausea and vomiting, fever, chills, yellowish skin or yellow discoloration of the whites of the eyes, or clay-colored stools may be experiencing a gallbladder attack. These attacks can sometimes follow fatty meals or happen at night. Anyone experiencing these symptoms should see a doctor immediately as these can be an indication of a large gallstone or other condition.
If you are going to start your first cycle soon, 'how to inject' is probably that last thing that you are worried about. You would have started by conducting research on the different injectable anabolic steroids available in the market, whichyou think can help you reach your goal. But when you have the vials and the syringes in front of you, you will surely think about how you will get the steroid out from the bottle and into your body. At this point, some people will become exasperated and even give up. Here is some information on injecting anabolic steroids.