The next year, Bonds's offensive production reached even higher levels, breaking not only his own personal records but several major league records. In the Giants' first 50 games in 2001, he hit 28 home runs, including 17 in May—a career high.  This early stretch included his 500th home run hit on April 17 against Terry Adams of the Los Angeles Dodgers .   He also hit 39 home runs by the All-star break (a major league record), drew a major league record 177 walks, and had a .515 on-base average, a feat not seen since Mickey Mantle and Ted Williams over forty years earlier. Bonds's slugging percentage was a major league record .863  (411 total bases in 476 at-bats), and, most impressively, he ended the season with a major league record 73 home runs. 
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In January 2004, Major League Baseball announced a new drug policy which originally included random, offseason testing and 10-day suspensions for first-time offenders, 30-days for second-time offenders, 60-days for third-time offenders, and one year for fourth-time offenders, all without pay, in an effort to curtail performance-enhancing drug use (PED) in professional baseball. This policy strengthened baseball's pre-existing ban on controlled substances , including steroids, which has been in effect since 1991.  The policy was to be reviewed in 2008, but under pressure from the . Congress , on November 15, 2005, players and owners agreed to tougher penalties; a 50-game suspension for a first offense, a 100-game suspension for a second, and a lifetime ban for a third.