Because the ultimate goal of a steroid cycle is to increase strength and muscle size, the associated spike in estrogen which accompanies steroids such as Testosterone is considered undesirable. In order to disassociate the two effects, two classes of drug are used. Medications such as Nolvadex or Clomid target the estrogen receptors. They make it more difficult for the estrogen to exert it’s influence within the body thus allowing the testosterone to act more freely. The second class is aromatase inhibitors such as Femara. They target the aromatase enzyme itself in order to prevent the production of estrogen in the first place. Sometimes, it’s not always clear which option you should go with or even what the differences are between the two. Lets clear that up a little.
Oxandrolone is rapidly absorbed from the gastrointestinal tract, resulting in a maximum plasma concentration between 30 and 90 minutes and a plasma half-life of about 9 hours. Oxandrolone has been given orally in the treatment of constitutional delayed growth and puberty in boys. Courses of treatment are short (about 3 to 4 months) because of the risk of epiphyseal closure. Oxandrolone has been prescribed to post-menopausal women in the treatment of osteoporosis. Oxandrolone is also under investigation in the treatment of Turner's syndrome in girls. As oxandrolone is C17-alpha-alkylated there is the potential for liver damage.