The cited “steroid pump” manifests itself after the intake of oxymetholone in an extreme form and the athlete experiences a corresponding feeling during his training. The high-level androgenic effect of oxymetholone stimulates the regeneration of the body so that it is unlikely to override. The athlete often has the feeling that he can start again from the beginning hours after a strenuous workout. The training pauses can be massively reduced. Here dangers await the joints and bones, which are not accustomed to this stress. Joint pain due to excessive weight is not a rarity.
The reason why Anapolon is still used in professional and competitive bodybuilding today is that Anapolon is considered a strong IGF-1 trigger, which means that the intake of anapolone increases IGF-1 production. IGF-1 is a very strong anabolic hormone.
Hot melt extrusion is utilized in pharmaceutical solid oral dose processing to enable delivery of drugs with poor solubility and bioavailability. Hot melt extrusion has been shown to molecularly disperse poorly soluble drugs in a polymer carrier increasing dissolution rates and bioavailability. The process involves the application of heat, pressure and agitation to mix materials together and ‘extrude’ them through a die. Twin-screw high shear extruders blend materials and simultaneously break up extruded particles can then be blended and compressed into tablets or filled into capsules.